本ben病bing主zhu要yao從cong呼hu吸xi道dao中zhong排pai毒du，經jing空kong氣qi飛fei沫mo傳chuan染ran給gei易yi感gan雞ji。此ci外wai還hai通tong過guo汙wu染ran的de飼si料liao，飲yin水shui，用yong具ju等deng，也ye可ke經jing消xiao化hua道dao感gan染ran。一yi年nian四si季ji均jun可ke發fa病bing，營ying養yang不bu足zu，密mi度du過guo高gao
，舍she溫wen過guo低di，氣qi溫wen突tu變bian通tong風feng不bu良liang等deng應ying激ji因yin素su可ke誘you發fa本ben病bing。各ge日ri齡ling均jun可ke感gan染ran，以yi雛chu雞ji最zui易yi感gan，且qie較jiao嚴yan重zhong。蛋dan雞ji在zai15日ri齡ling前qian感gan染ran本ben病bing會hui造zao成cheng輸shu卵luan管guan終zhong生sheng損sun傷shang，產chan蛋dan雞ji成cheng年nian後hou形xing成cheng假jia母mu雞ji

，輸shu卵luan管guan囊nang腫zhong，終zhong生sheng不bu產chan蛋dan。公gong雞ji發fa病bing率lv高gao於yu母mu雞ji，肉rou仔zai雞ji發fa病bing率lv高gao於yu產chan蛋dan雞ji
，這zhe可ke能neng與yu雞ji隻zhi的de生sheng長chang速su度du和he飼si料liao中zhong蛋dan白bai含han量liang有you關guan，蛋dan白bai越yue高gao生sheng長chang越yue快kuai死si亡wang率lv越yue高gao。